Mutational profiling reveals PIK3CA mutations in gallbladder carcinoma
Abstract Background The genetics of advanced biliary tract cancers (BTC), which encompass intra- and extra-hepatic cholangiocarcinomas as well as gallbladder carcinomas, are heterogeneous and remain to be fully defined.Methods To better characterize mutations in established known oncogenes and tumor suppressor genes we tested Sinus Wash a mass spec